Current Issue : January - March Volume : 2016 Issue Number : 1 Articles : 9 Articles
Objective.Women with infertility and recurrent miscarriages may have an overlapping etiology.The aim of this study was to compare\nthe pregnancy loss in pregnancies after IVF treatment with spontaneous pregnancies in women with recurrent miscarriages and to\nassess differences related to cause of infertility. Methods.The outcome from 1220 IVF pregnancies (Group I) was compared with 611\nspontaneous pregnancies (Group II) in women with recurrent miscarriages. Subgroup analysis was performed in Group I based\non cause of infertility: tubal factor (392 pregnancies); male factor (610 pregnancies); and unexplained infertility (218 pregnancies).\nResults.The clinical pregnancy loss rate in Group I (14.3%) was significantly lower than that of Group II (25.8%, ...
We report a case of a Somali refugeewho presented in the second trimester of her first pregnancy with a four-week history of gradual\nright-sided sensomotoric hemisyndrome including facial palsy and left-sided paresis of the oculomotorius nerve causing drooping\nof the left eyelid and double vision. Cranial magnetic resonance imaging revealed a solitary brainstem lesion. Upon detection of\nhilar lymphadenopathy on chest X-ray (CXR), the diagnosis of disseminated tuberculosis with involvement of the central nervous\nsystem was confirmed by PCR and treatment induced with rifampicin, isoniazid, pyrazinamide, and ethambutol.The patient had\na steady neurological improvement and a favorable pregnancy outcome....
Introduction. To investigate the effect of complex umbilical cord entanglement primarily around the trunk on pregnancy outcomes.\nMethods.We studied 6307 pregnant women with singleton pregnancies who underwent vaginal delivery of an infant at �37 weeks\nof gestation. Cases were classified into no cord, nuchal cord, and body cord groups and defined as cases without umbilical cord\nentanglement, one or more loops of the umbilical cord around the neck only, and umbilical cord around the trunk only, respectively.\nPregnancy outcomes were compared among these three groups. Results.The no cord, nuchal cord, and body cord group included\n4733, 1451, and 123 pregnancies, respectively. Although delivery mode was not significantly different among the three groups, 1-\nminute Apgar scores <7 and umbilical artery (UA) pH <7.10 were significantly more common in the umbilical cord entanglement\ngroups than in the no cord group. In particular, the frequency of 5-minute Apgar scores <7 was significantly higher (...
Aim : Several epidemiological studies have demonstrated the relationship between\nthe existence of fibroids and the occurrence of infertility, indeed fibroids have been\nreported in 25-30% of infertile women and are responsible for them alone to 2 to 3%\nof infertility cases when no other cause was found. The objective of this study was\nto investigate the probable association between the presence of a fibroid and the\noccurrence of infertility in the region of Sidi bel Abbes, west of Algeria.\nMethods: In order to determine the correlation between uterine fibroids and female\ninfertility, we performed a retrospective study including 83 patients operated for\nfibroids in the Maternity Hospital of Sidi Bel Abbes during the period May 2011-\nMay 2012. Results : The study showed that the most affected group of women are the ones\naged between 40-49 years old, 51.81 % of them were nulliparous and we found a\npredominance of patients with early age of menarche (77.11 %), 3.71 % of the\nwomen affected had a family history of fibroids. 49.16 % (29 cases) suffered from\nsterility, which 33.89 % were primary infertility and 15.25% secondary infertility.\nwe also found that the association between fibroids and infertility concerns more\nnulliparous women whose infertility is primary.\nWe also found an association with infertility and fibroids with age; the older the\nwomen become the more her fertility potential decreases and the more increased risk\nfor her to suffer from fibroids. Concerning spontaneous abortions we found that\nthey were more frequent in women with at least one fibroid associated with\nsecondary infertility\nConclusion: In our study we found that 49.16% of the patient�s suffered from\nsub fertility, so the association between fibroids and female infertility is not\nuncommon, it would be interesting to investigate the possible interactions between\nthis disease and infertility and the various mechanisms by which uterine fibroids can\ncause infertility....
Objective: The aim of this study was to determine maternal and perinatal complications of pregnancies\ncomplicated by severe preeclampsia in three tertiary care centers in Cameroon. Methods:\nWe carried out a descriptive cross sectional study from the 1st of June 2012 to the 31th of June\n2014, among pregnant women with severe preeclampsia followed up in three tertiary level hospitals\nin Yaound�©, Cameroon: the Yaound�© General Hospital, the Yaound�© Central Hospital, and the\nYaound�© University Hospital. Statistical analysis was performed using EPI 3.5.5. Data were described\nas means �± standard deviation, percentages and numbers. Chi-square and Fisher exact\ntests were used where appropriate. Results: Of the 2500 deliveries registered during the study period,\n111 cases (8.49%) were managed as severe preeclampsia. Four patients refused to participate\nand were excluded from the study. Most of these patients were non workers (58.0%), pauciparous\n(61.7%) and young (median age of 27.47 years �± 6.46). Eclampsia (12.14%), abruptio placentae\n(11.21%) and hypertensive retinopathy (7.47%) were the most frequent maternal complications.\nTwo cases (1.86%) of maternal deaths occurred in patients who had eclampsia. Prematurity\n(48.6%), intra uterine fetal death (13.1%) and oligoamnios (11.2%) were the most frequent\nfetal complications. All four neonatal deaths occurred in women in whom the diagnosis of severe\npreeclampsia was done between 28 and 33 weeks of gestation. Conclusion: Pregnancies complicated\nby severe preeclampsia had significantly high maternal and perinatal morbidity and mortality\nin Cameroon. The complications of severe preeclampsia can be prevented by more widespread use of antenatal care, education of primary medical care personnel, prompt diagnosis of high-risk\npatients and timely referral to tertiary medical centers. Pregnancy, Hypertension, Severe Preeclampsia, Maternal and Perinatal Complications, Cameroon...
Background: The metabolic syndrome affects more and more global people. Although it shows increasing\nprevalence in general population, the syndrome affects more women than men, what\nmakes its risk of being developed during pregnancy period. Also, possible perinatal adverse effects\nare always lurking. Objective: the objective was demonstrated what�s new in literature on\nmetabolic syndrome and pregnancy. Methods: A literature review was performed to extract the\narticles published on metabolic syndrome and pregnancy, its prevalence, obstetrical complications\nand its perinatal adverse effects. This review was conducted by online researching in\nPubMed, Lilacs, Medline, Embase, Scopus, Medscape, Libertas Academica and CINAHL database,\nScience database and also by researches in books. 27 selected articles on metabolic syndrome after\nthis research were all published between 1988 and 2015. Results: Among those 27 articles and\ntwo books studied, SM rate in obstetric population ranged from 3% to 42% depending on the previously\nmanifested components of the syndrome, age and region. Women with previously manifested\ncomponents showed more adverse perinatal effects. Conclusion: Women with pregesta-tional DM or SM and SM develop more during pregnancy, obstetric complications and adverse perinatal\noutcomes....
Resveratrol has aroused significant scientific interest as it has been claimed that it exhibits a spectrum of health benefits. These\ninclude effects as an anti-inflammatory and an antitumour compound.The purpose of this study was to investigate and compare\nany potential antigrowth effects of resveratrol and two of its derivatives, acetyl-resveratrol and polydatin, on 3D cell aggregates of\nthe EGFR/Her-2 positive and negative ovarian cancer cell lines SKOV-3 andOVCAR-8, respectively. Results showed that resveratrol\nand acetyl-resveratrol reduced cell growth in the SKOV-3 and OVCAR-8 in a dose-dependant manner.The growth reduction was\nmediated by the induction of apoptosis via the cleavage of poly(ADP-ribose) polymerase (PARP-1). At lower concentrations, 5 and\n10 ...
Objective. To test if serumhCGlevels themorning after the ovulatory hCG injection correlate with (1) retrieval efficiency, (2) oocyte\nmaturity, (3) embryo quality, (4) pregnancy, and/or (5) time to implantation in patients undergoing in vitro fertilization (IVF) with\nintracytoplasmic sperm injection (ICSI). Design. Retrospective cohort analysis. Setting. University-based IVF clinic. Patient(s). All\nIVF/ICSI cycles from April 2005 to February 2008 whose hCG administration was confirmed (...
Objective.The aim of this study was to describe critical care for obstetrical hemorrhage, especially in cases of uterine inversion. Study\nDesign. We extracted data for six patients diagnosed with uterine inversion concerning resuscitation. Results.The shock index on\nadmission of the six patients was 1.6 or more on admission. Four of the six experienced delay in diagnosis and received inadequate\nfluid replacement. Five of the six experienced delay in transfer. Five of the six underwent simultaneous blood transfusion on\nadmission, and the remaining patient experienced a delay of 30 minutes. All six patients successfully underwent uterine replacement\nsoon after admission. One maternal death occurred due to inappropriate practices that included delay in diagnosis, delay in\ntransfer, inadequate fluid replacement, and delayed transfusion. Two patients experiencing inappropriate practices involving delay\nin diagnosis, delay in transfer, and inadequate fluid replacement survived. Conclusion. If a delay in diagnosis occurs simultaneously\nwith a delay in transfer and inadequate fluid replacement, failure in providing a prompt blood transfusionmay be critical and result\nin maternal death.The monitoring of resuscitation with blood transfusion for uterine inversion is essential for the improvement of\nobstetrical care....
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